Concept: High performance liquid chromatography - mass spectrometry (HPLC-MS) in the analyticaltechnique vocabulary

Concept URI	http://dd.eionet.europa.eu/vocabulary/aq/analyticaltechnique/HPLC-MS
Preferred label	High performance liquid chromatography - mass spectrometry (HPLC-MS)
Definition	High performance liquid chromatography–mass spectrometry (HPLC-MS, or alternatively LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry. LC-MS is a powerful technique used for many applications which has very high sensitivity and selectivity. Generally its application is oriented towards the general detection and potential identification of chemicals in the presence of other chemicals (in a complex mixture). The limitations of LC-MS in urine analysis drug screening is that it often fails to distinguish between specific metabolites, in particular with hydrocodone and its metabolites.
Notation	HPLC-MS
Status	Valid
Status Modified	2013-03-22
Accepted Date	2013-03-22
Not Accepted Date